Lecture notes. Written from the material of MIT 8.591J 2004, licensed CC BY-NC-SA 4.0. Notes, not a transcript — reorganised and rewritten, carrying the same licence.
MIT 8.591J 2004¶
20 chapters, written from the course's material.
Contents¶
- Introduction to Systems Biology
- Cooperativity and the Lambda Switch
- The Lambda Phage Bistable Switch
- Molecular vs Systems Biology
- Mathematical basis of stability analysis
- Excitation and Adaptation in Chemotaxis
- Perfect Adaptation by Model Reduction
- Biological Oscillators
- Genetic Toggle Switch and Oscillator
- Stochastic Chemical Kinetics
- The Turing Instability Condition
- Stability of the Homogeneous Solution
- The LEGI Dispersion Relation
- Alternative views on gradient sensing
- Quorum Sensing and Cell-Cell Communication
- Drosophila Morphogen Gradients and Robustness
- Michaelis-Menten Kinetics and Cooperativity
- Genetic Switch in Phage Lambda
- Linear Stability of Fixed Points
- Master Equation for Gene Expression
Sources¶
The book carries CC BY-NC-SA 4.0.
| Offering | Original | Commit | Licence |
|---|---|---|---|
| MIT 8.591J 2004 | ocw.mit.edu/courses/8-591j-systems-biology-fall-2004/ | — | CC BY-NC-SA 4.0 |