Lecture notes. Written from the material of MIT 8.591J 2014, licensed CC BY-NC-SA 4.0. Notes, not a transcript — reorganised and rewritten, carrying the same licence.
MIT 8.591J 2014¶
24 chapters, written from the course's material.
Contents¶
- Feed-Forward Loops as Network Motifs
- Stochastic Gene Expression Bursts
- Lotka-Volterra Dynamics and Population Waves
- When Does Clonal Interference Matter
- Cost-Benefit Optimization and Statistical Evidence
- Evolutionary Paths and Game Theory
- Anticipatory Regulation and Bet Hedging
- Virulence Evolution and the Red Queen
- Robustness in Bacterial Chemotaxis
- Single Molecules and Protein Bursts
- Clonal Interference and Fitness Landscapes
- Three Views of Stochastic Kinetics
- From Genes to Ecosystems
- Toggle Switches and Stability Analysis
- The Moran Process and Fixation
- Tipping Points and Species Competition
- Binding, Kinetics, and Ultrasensitivity
- Neutral Theory of Species Abundance
- Relaxation Oscillators and Scale-Free Networks
- Diffusion and Pattern Formation
- Autoregulation and Molecular Titration
- Diffusion, Uptake, and Bacterial Chemotaxis
- Predator-Prey Cycles and Their Fragility
- Negative Autoregulation and the Repressilator
Sources¶
The book carries CC BY-NC-SA 4.0.
| Offering | Original | Commit | Licence |
|---|---|---|---|
| MIT 8.591J 2014 | ocw.mit.edu/courses/8-591j-systems-biology-fall-2014/ | — | CC BY-NC-SA 4.0 |